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Year : 2013  |  Volume : 7  |  Issue : 2  |  Page : 59-65

Effect of low power diode laser 810 nm on TGF-β1 level in GCF in aggressive periodontitis

1 Department of Dental Laser Applications, National Institute of Laser Enhanced Sciences, Cairo University, Cairo, Egypt
2 Lecturer of Periodontology, Faculty of Oral and Dental Medicine, Cairo University, Cairo, Egypt
3 Lecturer of Clinical Pathology, Faculty of Medicine, Cairo University, Cairo, Egypt
4 Bachelor of Dental Surgery, October 6th University, Cairo, Egypt

Correspondence Address:
Ramiz Radwan
Master Student, Medical Laser Applications, National Institute of Laser Enhanced Sciences, Cairo University, Giza
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0976-2868.124266

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Objective: To evaluate the effect of low power diode laser (LPDL) 810 nm as an adjunct to nonsurgical treatment of mild to moderate aggressive periodontitis (AgP). Background: AgP is a rapidly progressive severe form of periodontitis; conventional treatment depends on the concept of plaque control and bacterial eradication. Scaling and root planning (SRP) is the basic periodontal treatment, has its limitations, so new treatment modalities are needed. Materials and Methods: The use of low power laser was suggested as an adjunct to periodontal treatment, as it was proven earlier to have a positive biomodulatory effect on biological tissues if suitable parameters were used for the condition in hand. A split-mouth design clinical trial was performed. The laser group received both SRP plus laser, and the control group only received SRP. The clinical evaluation included periodontal pocket depth (PPD), clinical attachment loss (CAL), plaque index (PI), modified gingival index (MGI), and gingival recession (GR), were taken at baseline and at 3 months. Transforming growth factor beta 1 (TGF-β1) was screened by sampling gingival crevicular fluid (GCF) at baseline and at 1, 2, 3, and 4 weeks after treatment. Results: Showed a significant decrease of PPD and CAL in favor of laser group. PI, MGI, and GR showed no significant difference between both groups. TGF-β1 mean percentage showed a significant steady decrease in the laser group. Conclusion: Low power laser parameters in this clinical trial can be used as an adjunct to SRP in treatment of mild to moderate AgP.

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